NPHS2

Renal System · Glomerular Filtration Barrier

How does podocin support the kidney's filtration barrier?

NPHS2 encodes podocin, which is found at the contact region between podocytes. It helps support the specialized filter that separates the bloodstream from forming urine.

Common Gene Name: NPHS2 stomatin family member, podocin
NCBI Gene ID: 7827
Chromosome: 1

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

NCBI Gene — 7827
MedlinePlus Genetics — nphs2

Explore supporting evidence (1 records)

Condition or drug	Evidence	Grade / status	Context	Source
Congenital nephrotic syndrome	MedlinePlus related condition	Association type varies; no grade assigned here		View source 2016-07

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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