NTRK1
Nervous System · Neuropeptide & Neurotrophin Signaling
Why is NTRK1 important for sensing pain and temperature?
NTRK1 makes a receptor that supports the development and survival of sensory neurons. These cells carry information about sensations such as pain, temperature, and touch.
- Common Gene Name
- neurotrophic receptor tyrosine kinase 1
- NCBI Gene ID
- 4914
- Chromosome
- 1
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| hereditary sensory and autonomic neuropathy type 4 | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2021-11-17 |
| Congenital insensitivity to pain with anhidrosis | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2011-05 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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