PAPPA

Reproductive System · Implantation & Placental Function

How can PAPPA change the availability of a growth factor?

PAPPA makes an enzyme that cuts proteins holding insulin-like growth factors. Releasing those factors allows them to interact with receptors involved in growth and tissue responses.

Common Gene Name: pappalysin 1
NCBI Gene ID: 5069
Chromosome: 9

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

NCBI Gene — 5069

Explore supporting evidence (0 records)

No additional curated records were matched in this dataset. This does not mean that no evidence exists.

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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