PDE5A

Cardiovascular System · Vascular Smooth Muscle Contraction

Does having a PDE5A finding mean a PDE5 drug will help me?

PDE5A makes an enzyme that breaks down cGMP, a signal involved in smooth-muscle relaxation. Being the gene behind a drug target does not make a consumer DNA finding a treatment indication.

Common Gene Name: phosphodiesterase 5A
NCBI Gene ID: 8654
Chromosome: 4

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

NCBI Gene — 8654

Explore supporting evidence (0 records)

No additional curated records were matched in this dataset. This does not mean that no evidence exists.

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

← Back to Cardiovascular System