PICALM

Universal Cellular Machinery · Vesicular Trafficking & Secretory Exocytosis

How do cells package material into small transport vesicles?

PICALM encodes a protein that helps assemble clathrin-coated pits at membranes. These structures support uptake and recycling of material, including at nerve-to-muscle connections.

Common Gene Name: phosphatidylinositol binding clathrin assembly protein
NCBI Gene ID: 8301
Chromosome: 11

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

NCBI Gene — 8301

Explore supporting evidence (0 records)

No additional curated records were matched in this dataset. This does not mean that no evidence exists.

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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