PINK1

Universal Cellular Machinery · Autophagy & Lysosomal Degradation

Why is PINK1 discussed in relation to mitochondria?

PINK1 makes a kinase associated with the cell's energy-producing mitochondria. Its role in mitochondrial biology helps explain interest in neurological disease, while a particular variant still requires specific interpretation.

Common Gene Name: PTEN induced kinase 1
NCBI Gene ID: 65018
Chromosome: 1

Clinical Evidence Status

Established disease relationship

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

NCBI Gene — 65018
MedlinePlus Genetics — pink1

Explore supporting evidence (1 records)

Condition or drug	Evidence	Grade / status	Context	Source
Parkinson disease	ClinGen gene-disease validity	Definitive	Autosomal recessive	View source 2023-01-18

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

← Back to Universal Cellular Machinery