PLCG2
Universal Cellular Machinery · Phosphoinositide & Lipid Second Messenger Signaling
How do immune cells translate receptor activity into internal messengers?
PLCG2 makes an enzyme that performs a lipid reaction used in signal transmission. These signals help coordinate the growth, maturation, and movement of cells such as B cells and mast cells.
- Common Gene Name
- phospholipase C gamma 2
- NCBI Gene ID
- 5336
- Chromosome
- 16
Clinical Evidence Status
Clinical utility not established here
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (1 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| PLCG2-associated antibody deficiency and immune dysregulation | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2019-08 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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