PNPLA3
Universal Cellular Machinery · Core Enzymatic Catalysis & Cofactor Chemistry
Does a PNPLA3 finding prove that I have fatty liver?
PNPLA3 encodes an enzyme involved in fat handling in liver and fat cells. Risk-associated variants do not establish the presence or severity of liver disease, which needs clinical assessment.
- Common Gene Name
- patatin like domain 3, 1-acylglycerol-3-phosphate O-acyltransferase
- NCBI Gene ID
- 80339
- Chromosome
- 22
Clinical Evidence Status
Clinical utility not established here
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (1 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Metabolic dysfunction-associated steatotic liver disease | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2026-04 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
← Back to Universal Cellular Machinery