POLD2
Universal Cellular Machinery · DNA Replication & Telomere Maintenance
How does POLD2 support copying and repairing DNA?
POLD2 makes a subunit of DNA polymerase delta that supports the enzyme complex's activity. The complex is used in DNA replication and repair, rather than functioning as a stand-alone cancer test.
- Common Gene Name
- DNA polymerase delta 2, accessory subunit
- NCBI Gene ID
- 5425
- Chromosome
- 7
Clinical Evidence Status
Disease evidence limited or conflicting
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (1 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| non-severe combined immunodeficiency due to polymerase delta deficiency | ClinGen gene-disease validity | Limited | Autosomal recessive | View source 2026-02-19 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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