POMC
Metabolic System · Energy Balance, Appetite & Thermogenesis
Why can POMC affect more than one hormone pathway?
POMC makes a large precursor that is cut into several signaling peptides. Those products have different roles, linking one gene to multiple processes including hormonal and appetite regulation.
- Common Gene Name
- proopiomelanocortin
- NCBI Gene ID
- 5443
- Chromosome
- 2
Clinical Evidence Status
Tumor or drug-label biomarker context
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Proopiomelanocortin deficiency | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2014-02 | |
| Setmelanotide (3) | FDA labeling biomarker | Label mentions biomarker; actionability not inferred | Endocrinology | View source |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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