SCN10A
Sensory System · Nociception & Thermal Sensation
What helps pain-sensing nerve cells generate an electrical signal?
SCN10A makes part of the NaV1.8 sodium channel in sensory neurons. Sodium movement through these channels contributes to the electrical activity used to transmit pain signals.
- Common Gene Name
- sodium voltage-gated channel alpha subunit 10
- NCBI Gene ID
- 6336
- Chromosome
- 3
Clinical Evidence Status
Disease evidence limited or conflicting
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Brugada syndrome | ClinGen gene-disease validity | Disputed | Autosomal dominant | View source 2025-09-10 |
| Small fiber neuropathy | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2012-11 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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