SFTPA1

Respiratory System · Alveolar Surfactant Metabolism

Can a surfactant protein also help defend the lungs?

SFTPA1 makes surfactant protein A1, which can recognize certain carbohydrate patterns on microbes. It contributes to lung defense as well as the maintenance of the surfactant system.

Common Gene Name
surfactant protein A1
NCBI Gene ID
653509
Chromosome
10

Clinical Evidence Status

Disease evidence limited or conflicting

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (1 records)
Condition or drugEvidenceGrade / statusContextSource
interstitial lung disease 1ClinGen gene-disease validityModerateAutosomal dominantView source
2025-01-28

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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