SFTPC
Respiratory System · Alveolar Surfactant Metabolism
What does surfactant protein C do for breathing?
SFTPC encodes a protein in the surfactant layer lining the lung's air sacs. The mixture reduces surface tension so the sacs can remain open and refill more easily.
- Common Gene Name
- surfactant protein C
- NCBI Gene ID
- 6440
- Chromosome
- 8
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (3 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| SFTPC-related interstitial lung disease | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2024-07-16 |
| Idiopathic pulmonary fibrosis | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2012-07 | |
| Surfactant dysfunction | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2012-07 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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