SLC34A1

Renal System · Tubular Reabsorption, Electrolyte Transport & Urine Concentration

How do the kidneys keep useful phosphate from being lost?

SLC34A1 encodes a sodium-dependent phosphate transporter in kidney cells. It supports phosphate reabsorption, helping preserve a mineral needed for bones, energy metabolism, and cellular signaling.

Common Gene Name
solute carrier family 34 member 1
NCBI Gene ID
6569
Chromosome
5

Clinical Evidence Status

Established disease relationship

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (3 records)
Condition or drugEvidenceGrade / statusContextSource
hypercalcemia, infantile, 2ClinGen gene-disease validityDefinitiveAutosomal recessiveView source
2022-10-19
Fanconi renotubular syndrome 2ClinGen gene-disease validityDisputedAutosomal recessiveView source
2022-09-06
Idiopathic infantile hypercalcemiaMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2017-12

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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