SLC46A1
Gastrointestinal & Hepatic System · Intestinal Nutrient Absorption
Why might folate absorption matter even when someone eats enough?
SLC46A1 makes a transporter that brings folates into cells, including those lining the small intestine. Severe transporter defects can interfere with folate uptake, so dietary intake and the body's ability to absorb it are separate issues.
- Common Gene Name
- solute carrier family 46 member 1
- NCBI Gene ID
- 113235
- Chromosome
- 17
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (1 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| hereditary folate malabsorption | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2026-07-16 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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