SOST
Musculoskeletal System · Bone Remodeling
Why would the body deliberately limit new bone formation?
SOST encodes sclerostin, a signal produced by bone cells that restrains bone formation. Bone maintenance depends on balancing new tissue production with removal of older tissue.
- Common Gene Name
- sclerostin
- NCBI Gene ID
- 50964
- Chromosome
- 17
Clinical Evidence Status
Clinical utility not established here
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (1 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| SOST-related sclerosing bone dysplasia | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2009-06 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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