SOX10

Nervous System · Myelination & Glial Trophic Support

Why might SOX10 have effects across several developing tissues?

SOX10 makes a DNA-binding regulator that directs selected developmental programs. Such regulators affect the identity and maintenance of cells, so their consequences can extend beyond one organ.

Common Gene Name
SRY-box transcription factor 10
NCBI Gene ID
6663
Chromosome
22

Clinical Evidence Status

Established disease relationship

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (4 records)
Condition or drugEvidenceGrade / statusContextSource
Waardenburg syndrome type 4CClinGen gene-disease validityDefinitiveAutosomal dominantView source
2018-06-19
Waardenburg syndromeMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2022-08
Kallmann syndromeMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2022-08
Hirschsprung diseaseMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2022-08

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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