STAT5B
Reproductive System · Mammary Development & Lactogenesis
What connects STAT5B with responses to growth hormone?
STAT5B encodes a signaling regulator that responds to growth hormones and several immune signals. It carries those messages into changes in gene activity needed for the cell's response.
- Common Gene Name
- signal transducer and activator of transcription 5B
- NCBI Gene ID
- 6777
- Chromosome
- 17
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| growth hormone insensitivity with immune dysregulation 1, autosomal recessive | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2025-12-16 |
| growth hormone insensitivity syndrome with immune dysregulation 2, autosomal dominant | ClinGen gene-disease validity | Moderate | Autosomal dominant | View source 2026-01-20 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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