STK11
Universal Cellular Machinery · Phosphorylation & Kinase Signaling Cascades
How does STK11 connect growth control with cellular energy use?
STK11 makes a kinase that helps regulate cell organization and energy-related responses. These activities contribute to its role in restraining inappropriate growth.
- Common Gene Name
- serine/threonine kinase 11
- NCBI Gene ID
- 6794
- Chromosome
- 19
Clinical Evidence Status
Actionability report availableEstablished disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (7 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Peutz-Jeghers syndrome | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2023-12-20 |
| familial ovarian cancer | ClinGen gene-disease validity | No Known Disease Relationship | Autosomal dominant | View source 2016-10-26 |
| Breast cancer | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2015-05 | |
| Ovarian cancer | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2015-05 | |
| Lung cancer | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2015-05 | |
| Peutz-Jeghers Syndrome | ClinGen clinical actionability | Scored report; not a validity grade | Adult | View source 2022-02-09 |
| Peutz-Jeghers Syndrome | ClinGen clinical actionability | Scored report; not a validity grade | Pediatric | View source 2022-02-09 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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