TCF7L2
Metabolic System · Insulin Signaling & Glucose Homeostasis
Does a TCF7L2 risk variant mean diabetes is inevitable?
TCF7L2 regulates genes in the Wnt pathway and is linked to blood-glucose regulation. Some variants affect type 2 diabetes susceptibility, but they do not determine an individual's future diagnosis.
- Common Gene Name
- transcription factor 7 like 2
- NCBI Gene ID
- 6934
- Chromosome
- 10
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (1 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| complex neurodevelopmental disorder | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2021-12-15 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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