TNNI3

Cardiovascular System · Myocardial Contractility & Sarcomeric Assembly

Is TNNI3 the same thing as the troponin measured after chest pain?

TNNI3 encodes cardiac troponin I, a protein that helps regulate heart-muscle contraction. A genetic test examines its DNA instructions, while a troponin blood test measures protein released into the circulation.

Common Gene Name
troponin I3, cardiac type
NCBI Gene ID
7137
Chromosome
19

Clinical Evidence Status

Actionability report availableEstablished disease relationship

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (8 records)
Condition or drugEvidenceGrade / statusContextSource
arrhythmogenic right ventricular cardiomyopathyClinGen gene-disease validityNo Known Disease RelationshipAutosomal dominantView source
2019-07-16
hypertrophic cardiomyopathyClinGen gene-disease validityDefinitiveAutosomal dominantView source
2017-09-05
dilated cardiomyopathy 1FFClinGen gene-disease validityStrongAutosomal dominantView source
2026-03-04
dilated cardiomyopathy 2AClinGen gene-disease validityStrongAutosomal recessiveView source
2026-03-04
Familial restrictive cardiomyopathyMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2013-02
Nonsyndromic hypertrophic cardiomyopathyMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2013-02
Nonsyndromic dilated cardiomyopathyMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2013-02
Familial Hypertrophic CardiomyopathyClinGen clinical actionabilityScored report; not a validity gradeAdultView source
2026-07-22

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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