TPH2

Gastrointestinal & Hepatic System · Gastrointestinal Motility & Enteric Plexus

Can TPH2 tell me whether I have low serotonin?

TPH2 encodes an enzyme that performs an early, limiting step in serotonin production. A genetic result does not directly measure brain serotonin or identify the cause of a mood disorder.

Common Gene Name: tryptophan hydroxylase 2
NCBI Gene ID: 121278
Chromosome: 12

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

NCBI Gene — 121278

Explore supporting evidence (0 records)

No additional curated records were matched in this dataset. This does not mean that no evidence exists.

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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