TPO

Endocrine System · Thyroid Hormone Synthesis & Action

Does a TPO genetic finding mean I have thyroid antibodies?

TPO encodes thyroid peroxidase, an enzyme that helps incorporate iodine during thyroid-hormone production. A DNA variant and an anti-TPO antibody result measure different things, so one cannot substitute for the other.

Common Gene Name: thyroid peroxidase
NCBI Gene ID: 7173
Chromosome: 2

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

NCBI Gene — 7173
MedlinePlus Genetics — tpo

Explore supporting evidence (1 records)

Condition or drug	Evidence	Grade / status	Context	Source
Congenital hypothyroidism	MedlinePlus related condition	Association type varies; no grade assigned here		View source 2015-09

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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