UMOD
Renal System · Tubular Reabsorption, Electrolyte Transport & Urine Concentration
What does uromodulin do in the kidney?
UMOD makes uromodulin, a protein produced in a specific region of the kidney tubule. It participates in the local environment that supports salt handling and normal urinary function.
- Common Gene Name
- uromodulin
- NCBI Gene ID
- 7369
- Chromosome
- 16
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| autosomal dominant medullary cystic kidney disease with or without hyperuricemia | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2021-01-13 |
| Autosomal dominant tubulointerstitial kidney disease-UMOD | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2024-08 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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