UPK2

Renal System · Urothelial Barrier Integrity

How does the bladder lining withstand stretching as it fills?

UPK2 encodes a protein in the plaques that reinforce the urinary lining. This specialized surface helps the bladder accommodate distention while maintaining its barrier.

Common Gene Name: uroplakin 2
NCBI Gene ID: 7379
Chromosome: 11

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

NCBI Gene — 7379

Explore supporting evidence (0 records)

No additional curated records were matched in this dataset. This does not mean that no evidence exists.

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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