UPK3A
Renal System · Urothelial Barrier Integrity
What does UPK3A contribute to the bladder's protective layer?
UPK3A makes a uroplakin that assembles with other membrane proteins on bladder-lining cells. Together they form surface structures suited to the urinary tract's protective function.
- Common Gene Name
- uroplakin 3A
- NCBI Gene ID
- 7380
- Chromosome
- 22
Clinical Evidence Status
Disease evidence limited or conflicting
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (1 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| congenital anomaly of kidney and urinary tract | ClinGen gene-disease validity | Disputed | Autosomal dominant | View source 2023-01-09 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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