USH2A
Sensory System · Phototransduction & Retinal Processing
Why can USH2A be relevant to both hearing and vision?
USH2A makes usherin, a protein present in supporting structures in the inner ear and retina. Its use in both tissues helps explain why certain pathogenic variants can affect more than one sense.
- Common Gene Name
- usherin
- NCBI Gene ID
- 7399
- Chromosome
- 1
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (3 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Usher syndrome type 2 | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2017-02-15 |
| Usher syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2016-05 | |
| Retinitis pigmentosa | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2016-05 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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